Side effects, drug interactions, warnings, precautions, dosing, storage, pregnancy, and breastfeeding safety information is included. Orphenadrine citrate injection orphenadrine citrate dose. This table can be used for ysite compatibility at the usual manufacturers concentrations. Orphenadrine the brand norflex has been discontinued in the us is a prescription drug used to treat acute muscle aches, pains, or spasms. Norflex are white tablets with nx on one side and no markings on the other side, in bottles containing 100 tablets. Orphenadrine citrate injection is a sterile aqueous solution of orphenadrine citrate.
Combinations of two, three or more of these drugs occasionally need to be coadministered via. Orphenadrine should be used cautiously in patients with hepatic disease, renal impairment, or renal disease. Draft guidance on orphenadrine citrate this draft guidance, once finalized, will represent the food and drug administrations fdas current thinking on this topic. To access the iv compatibility module, open the lexicomp app and select the iv compatibility icon from the home page. Norflex belongs to a group of drugs called skeletal muscle relaxants. Each norflex extendedrelease tablet contains 100 mg orphenadrine citrate. The court also ruled that a capped ne edle that falls on the floor will not cause harm to. However, in some circumstances there may be compelling reasons for mixing two or more parenteral drug solutions in the same infusion bag, in the same syringe or at a ysite junction. Psychotropic injectable chart medication compatibility for. Vchphc revised june 2009 syringe compatibility chart use within 15 minutes atropine benztropine chlorpromazine codeine dimenhydrinate diphenhydramine droperidol fentanyl glycopyrrolate haloperidol hydromorphone hydroxyzine lorazepam meperidine methotrimeprazine metoclopramide midazolam morphine prochlorperazine.
It is used to treat muscle pain and to help with motor control in parkinsons disease, but has largely been superseded by newer drugs. Norflex pharmacokinetics absorption bioavailability. Norflex orphenadrine injection side effects, images. Syringe driver drug compatibilities guide to practice 20.
Norflex definition of norflex by medical dictionary. A patient must have a central line available to receive these. Webmd provides common contraindications for norflex injection. Read more about the prescription drug orphenadrine injection. You should also ensure that the drugs checked are compatible in terms of carrier fluid this table gives information for two drug combinations only. To minimize adverse reactions after parenteral administration of the drug, patient should be assisted from recumbent position.
It occurs as a white, crystalline powder having a bitter taste. Palliative care there are a number of drugs that are commonly delivered via syringe driver to patients having palliative care in the community see box. Intravenous iv preparation and infusion guidelines globalrph. Safety and effectiveness in pediatric patients have not been established. Guidelines from the american family physicians list ampicillin. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures. Taking norflex orphenadrine with alcohol or narcotics can worsen the drowsiness. The drug is metabolized by the liver and the resultant metabolites as well as unchanged drug are excreted in the kidneys.
The eastern metropolitan region palliative care consortium emrpcc grants permission to reproduce parts of this publication for clinical and educational use only, provided that the emrpcc is acknowledged. Patient should remain in this position for 510 min postinjection. This medication comes in an injectable form to be given into the vein iv or into the muscle im by a healthcare provider. These work by changing the way the body senses muscle pain. Trissels 2 clinical pharmaceutics database clinical. Norflex orphenadrine dosing, indications, interactions. Consumer information about the medication orphenadrine injection norflex, includes side effects, drug interactions, recommended dosages, and storage information. Orphenadrine may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle. Norflex orphenadrine can make you sleepy or drowsy. Norflex fda prescribing information, side effects and uses. An order yesterday read to give toradol 30mg and morphine 10mg im to a pt in narcotic withdrawal. C indications adjunct to rest and physical therapy in the treatment of muscle spasm associated with acute painful musculoskeletal.
This reference contains standard dilutions including iv admixture drug concentration, infusion volumes, and infusion rates. Each norflex extendedrelease tablet contains 100 mg orphenadrine. Thames valley ysite intravenous drugs compatibility chart. Find patient medical information for norflex injection on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Mixing solutions of parenteral drugs is generally not recommended because of the potential for incompatibility and consequent loss of activity of one or both drugs.
Drugs az pill identifier supplements symptom checker diseases dictionary media. Compatibility of micafungin injection with other drugs during simulated ysite coadministration abstract the objective of this study was to evaluate the physical compatibility of micafungin injection with selected other drugs during simulated ysite coadministration. You can download lab tests from element materials technology in pdf format. That is just to observe for any acuteallergic reactions. Adverse reactions of orphenadrine are mainly due to the mild anticholinergic action of orphenadrine, and are usually associated with higher dosage.
The recommended dose is 150 mgkgday to 200 mgkgday iv divided every 4 to 6 hours. Ysite injection drug compatibility chart for general wards. He was a tough pt so i consulted the charge rn on how to best admin these meds. Syringe driver drug compatibilities guide to practice 20 july 20 these guidelines have been ed. Orphenadrine citrate is the citrate salt of orphenadrine and occurs as a white, crystalline powder having a bitter taste. Each monograph contains stability data, administration guidelines, and methods of preparation. Critical care intravenous drug administration guide. Ingredients each norflex tablet contains 100mg orphenadrine citrate. If you have more than one iv compatibility database downloaded on your app, you may be prompted to make a selection.
Intravenous administration of formulary medications. As far as things that might sedate, like opiates, or po flexeril, or norflex, patients either have to have a driver, or they can wait until the medication effect wears off. Norflex should be given to a pregnant woman only if clearly needed. In our health system, there is shot time 15 minutes for any im injection. Norflex side effects, uses, dosage, overdose, pregnancy. Find out what health conditions may be a health risk when taken with norflex injection.
Despite thorough checking, some entries might be false, especially as graphic card manufacturers occasionally. Always consult your doctor before taking these medications together. Taking orphenadrine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. This iv drug compatibility chart is provided as a quick reference, however since information is subject to change it is advised that you check with a pharmacist for recommendations as well as product information to check for any changes or additional incompatibilities. Orphenadrine citrate is the citrate salt of orphenadrine 2dimethylaminoethyl 2 methylbenzhydryl ether citrate. Dont drive or do anything that requires concentration until you know how it affects you. To mix or not to mix compatibilities of parenteral drug. Orphenadrine injection norflex side effects, medical.
Check tubing below ysite carefully for discoloration, cloudiness or precipitation blank do not mix. Norflex orphenadrine citrate injection graceway pharmaceuticals, llc effective date. Norflex injection contains 60 mg of orphenadrine citrate in aqueous solution in each ampul. Orphenadrine helps to relieve pain and stiffness in muscles and can treat muscle spasms. It can not be extrapolated to three drug combinations. Antispasticity agents have activity in upper motor syndromes e. Norflex orphenadrine can make you feel very tired or sleepy. Orphenadrine citrate should be used with caution in patients with tachycardia, cardiac decompensation, coronary insufficiency, cardiac. Do not take this medication if you are allergic to orphenadrine, or if you have problems with urination, an enlarged prostate, glaucoma, a blockage in your stomach or intestines, trouble. Draft guidance on orphenadrine citrate food and drug. Before taking orphenadrine, tell your doctor if you are taking any of the following medicines. And two physicians, one with academic credentials, backed up the nurse experts testimony that the two drugs in question are syringe compatible. The authors make no claims of the accuracy of the information contained herein. Use the search field above to look up prescription or otc drugs, and herbal supplements.
This iv drug compatibility chart is provided as a quick reference, however since information is subject to change. Compatibility depends upon many factors including temperature, ph, iv fluid, concentration, order of mixing and brand of drug. To use the trissels iv compatibility module, select the trissels iv compatibility option when prompted. Physical stability was assessed by both visual observation and turbidity. Orphenadrine sold under many brand names worldwide is an anticholinergic drug of the ethanolamine antihistamine class. It is intended for intravenous or intramuscular administration. Do not stop taking the medications without a physicians advice.
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